Concentrated Growth Factor (CGF) is used successfully in cosmetic and anti-aging applications and also provides effective results in wound healing and treatment of musculoskeletal diseases. Thanks to the intense growth effect provided by the method, it is possible to benefit more from the healing capacity of the blood.
What is CGF? How to Obtain?
CGF-CD34 is the abbreviation of the term concentrated growth factor and contains dense stem cells. This method is also known as 2nd Generation Platelet Concentrate and research has shown that stem cells called CD34 can be obtained with this method. The sample taken from the person's own blood is separated by a special centrifuge process and a layer containing platelets, leukocytes, various growth factors and cytokines is created. As a result of the subsequent activation processes, a plasma fluid containing dense growth factor and hematopoietic (blood-forming) stem cells is obtained.
How Many Sessions Does the CGF Procedure Take and When Does It Take Effect?
According to the comments and expert opinions of those who have had CGF treatment, 3-6 sessions of CGF treatment are generally sufficient. However, it should be noted that this specified period may vary from person to person. The effects can be felt after the first procedure. A healthy shine appears on the skin within a few days. After 3-6 sessions to be performed at intervals of 15-30 or 45-90 days throughout the year, repeating them 3-4 times a year ensures a continuous rejuvenating effect.
Who cannot receive CGF Treatment?
CGF treatment should not be applied to people whose blood tests show insufficient platelet count, in case of active infection, in people with bleeding diseases, if blood thinners were used on the same day, in those with chronic liver disease and in those with a history of cancer in the last 5 years.
What Should Be Considered After CGF?
It is recommended not to clean or wash the area receiving CGF treatment for 4-6 hours and not to apply make-up for 12-24 hours. Do not enter the sea or pool. Anti-inflammatory drugs should not be used as they will disrupt the natural healing process provided by CGF. When necessary, painkillers such as Paracetamol can be taken or cold compresses can be applied.
What is the Difference Between CGF and PRP?
The difference between CGF and PRP can be summarized as follows: PRP stands for Platelet Rich Plasma. CGF-CD34 treatment method is an advanced technique to obtain plasma containing more dense and concentrated growth factor and blood-forming hematopoietic stem cells (CD-34). CGF is more effective in all cases where PRP is used. It is the region where the healing power of blood is highest. It is not only applied directly to the tissue, but can also be administered intravenously by a specialist when necessary.
By Which Methods Is CGF Transaction Performed?
The more PRP process can produce platelet-rich plasma (PRP), the more platelets CGF process can activate. Platelets must be lysed by various additional methods to activate growth factors. This disruption process is carried out using methods such as radio frequency, physical bio-activators and chemical antagonists. While platelet density is increased by using PRP application, the growth and healing processes of platelets are triggered through the additional methods mentioned. CGF technique reveals the therapeutic, regenerative and repairing properties of these concentrated platelets.
What are the Effects of CGF Treatment?
Platelets containing activated concentrated growth factors especially activate damaged tissue repair mechanisms. Platelets contain significant amounts of growth factors. With the PRP technique and CGF technique used to obtain dense platelets, cell proliferation, collagen and hyaluronic acid production, epidermal cell growth and angiogenesis or similar restructuring systems are activated in the body and used in the treatment of various diseases. Since it has been understood that growth factors have many positive effects on tissue regeneration, PRP and CGF techniques have begun to be widely used. In this way, while the number of platelets is increased in the tissue damaged area with the PRP technique, the healing process of tissue damage is accelerated by releasing high-density growth factors with the CGF technique.
What are the Side Effects of CGF Treatment?
CGF, or concentrated growth factor therapy, is a treatment method that has gained popularity recently. However, like every medical procedure, CGF treatment has certain side effects. These side effects are usually mild and temporary. CGF treatment side effects are as follows:
- There is a risk of infection caused by microorganisms in the treated area. This risk may increase if sterile conditions are not provided.
- Bleeding or bruising may occur after the procedure. However, this situation is usually temporary and resolves in a short time.
- Mild pain and tenderness may be felt in the area where the treatment is applied. This situation usually returns to normal within a few days.
- Labor may occur, but this usually resolves within a few days.
- Although rare, some people may experience allergic reactions to CGF treatment.
If you experience any side effects or experience symptoms that cause you to worry, you should definitely consult your doctor. Remember, regular communication with your doctor before and after every medical procedure is the most effective way to prevent possible complications.
How is CGF Applied?
Using the PRP technique, the blood taken from the person is enriched with platelets. Then, when platelets are broken down with the CGF technique, concentrated growth factors are obtained. After the intensively concentrated plasma application area is disinfected and local anesthetic creams are applied, it is made ready for the procedure. Methods of making the concentrated plasma liquid suitable for treatment and applying it to the determined area include direct injection, microneedling, use as a mask, mesotherapy and applying to wound or tissue damaged areas. Thanks to the new method called CGF-CD34, which is the second generation application of CGF, not only dense growth factors but also stem cells called CD34 can be obtained from platelets.
What are the Application Areas of CGF?
The aging process is generally defined as long-term tissue damage. As we get older biologically, increasing damage to our tissues creates signs of aging. The aging process is chronic and various external factors also affect tissue damage in our body. Therefore, tissue repair mechanisms cannot fully detect this process. Tissue repair mechanisms normally work faster and more intensively during the repair of any damage or wound. Thanks to CGF application, in this slow tissue damage process, which tissue repair mechanisms cannot detect, the body's healing mechanism is imitated in cases of injury. For this reason, CGF procedures for aesthetic purposes are generally applied to areas such as the face, neck, hands, décolleté area, inner legs and cellulite areas, and arms.
- Joint calcifications (knee, hip, ankle, shoulder areas)
- Wounds in joint, ligament and muscle areas
- Meniscus injuries and tears
- Hernias in the waist and neck
- Chronic waist and neck pain
- Inflammatory muscle diseases and rheumatic conditions
- Muscle and connective tissue adhesion
- Heel spur problems
- Cartilage-bone wear and calcifications
- Wound and burn treatments
- Treatment of non-healing wounds and diabetic foot diseases
How Long Does the Cgf-Cd34 Effect Last?
The CGF method activates the body's own healing ability without using any drugs or pharmacological products. Thanks to this stimulation, the results are usually slow but permanent. After the first injection, a healthy skin glow becomes evident and overall benefits are seen. If the use is made 3-6 times at 15-30 or 45-90 day intervals and repeated 3-4 times a year, the effect of these treatments can provide permanent youth. 2 - 4 weeks after the first injection, the condition of the damaged tissue is re-examined and additional injections are planned if necessary.
Additional CGF-CD34 treatments may be needed for people who are in menopause at the 1-year follow-up, who smoke or consume alcohol, who do not pay attention to their diet, or who cannot protect their skin from sun and ultraviolet rays if there is trauma or infection in the area where CGF-CD34 is applied. However, if these harmful factors can be avoided, it is possible to wait 1 or 2 years for the second CGF-CD34 course.
It has been observed that some people experience only partial recovery, while others achieve complete recovery. Many scientific studies have stated that the success rate is 80 – 85%. Some studies have shown that the healing process continues even 6-9 months after treatment. However, if the factors that cause tissue damage are still present, it is inevitable that the damage will occur again. One week after the treatment, it is observed that the skin becomes brighter and lighter in color, and wrinkles soften from the second session.