PRP (Platelet Rich Plasma)

PRP, taken from the initials of the words Platelet Rich Plasma; Today, it is one of the biggest achievements in cellular therapy, which is one of the skin rejuvenation and hair loss treatment methods. Platelet means thrombocyte; Platelets are cells that exist in our blood. Their number is around 300,000 and their lifespan is 4 days. These cells perform the coagulation or fluidity properties of blood and the task of cleaning the wound site during healing processes. In addition, growth factors released from platelets activate the repair mechanism of cells and provide healing of wounds.

Anti-aging and PRP relationship;

Stimulating the skin with lights, lasers or chemical peels actually means triggering skin repair and rejuvenation with limited damage. In short, it stimulates the skin by pretending to cause very slight damage to the skin; activating the wound healing mechanism; It is a trigger to rejuvenate the skin.

Because cells take action after stimulation; production begins as if mimicking wound healing, collagen and elastic fibers are produced, circulation increases, the stimulated area of ​​the tissue is cleaned and purified; therefore, its color becomes lighter, its vessels are healed, and the health of the skin is restored to be better than before.

If the skin is not stimulated, it ages; What I want to emphasize here is that we can turn the years back and achieve anti-aging by stimulating the skin by using the right methods suitable for the skin, mechanical or chemical, with or without needles.

How effective is PRP alone? What are the results and how long does the effect last?

What is meant by the cellular therapy method is to encourage the cells to work and to give them the materials they need. Since this method provides the environment for growth factors that trigger the functioning of cells, it has an unchanging place in anti-aging and hair loss treatments. The adequacy of PRP treatment alone will vary according to the age, experience of the person applying it, and the visible and analyzed result of the skin. It is beneficial to do it even if the skin is sun-worn and sagging, or just looks lifeless and pale.

Are there any side effects of the treatment?

Since this treatment is autologous, that is, it is related to the reintroduction of one's own cells, there is no harm; however, in terms of expectations, it is appropriate for the practicing physician to support the patient with the right treatments, as necessary.

Does PRP Treatment Prevent Hair Loss?

For many people, hair is a reflection of personal style. If hair has been used as a part of your identity for most of your life, hair loss can put you in a really tough situation. But for some, a medical treatment called platelet-rich plasma (PRP) injections “PRP Treatment for Hair Loss” can change the fate of your hair.

How is PRP prepared?

PRP is an easy-to-apply treatment in which the patient's own blood is processed. A small sample of blood is taken from the patient (typically the arm) in a special tube and then placed in a centrifuge for 15 minutes. While inside, the tube is quickly turned to separate the plasma from the red blood cells. A special plasma portion (platelet-rich plasma) that is separated is then injected into the scalp with micro needling.

Benefits of Hair PRP Treatment

Since PRP application for hair loss acts as a nutrient for hair follicles, it supports the existing hair follicles and then encourages the growth of hair follicles that cannot grow due to insufficient nutrition on the scalp. It works especially well in "male pattern hair loss" and prevents hair follicles from shrinking and disappearing over time or prolongs the process.

The plasma separated from the blood during PRP treatment contains growth factors, which are a mixture of proteins and cytokines. Both of these factors play an important role in stimulating hair follicles for hair growth.

It is known that the growth factors in Hair PRP Treatment create the following effects:

• Epidermal Growth Factor: It regulates cell growth by stimulating keratin and fiber production.
• Growth Factor Conversion: Promotes the growth of new blood vessels.
• Vascular Endothelial Growth Factor: Stimulates the growth of blood vessels from the existing vascular system.
• Fibroblast Growth Factor: Supports granulation during tissue repair.
• Platelet-Derived Growth Factor: It attracts macrophages and fibroblasts to the treated area while promoting collagen growth and proteoglycan synthesis.
• Collagen Stimulating Growth Factor: Stimulates granulocyte and macrophage proliferation for the growth of healthy tissue and blood cells.
• Keratinocyte Growth Factor: Keratinocyte migration, differentiation and proliferation can optimize conditions for healing and formation of new skin.
• Interleukins, Macrophages, Keratinocytes, Endothelial Cells, Lymphocytes, Fibroblasts, Osteoblasts, Basophils and Mast Cells: Activates fibroblast differentiation and also induces collagen and proteoglycan synthesis for healthy cell generation and repair of damaged tissues.

How Does Hair PRP Treatment Work?

Platelet-Rich Plasma (PRP) contains high concentrations of more than 20 growth factors that are actively secreted from the α-granules of platelets. Factors thought to be effective in stimulating hair regrowth by PRP include platelet-derived growth factor, transforming growth factor, vascular endothelial growth factor (VEGF), epidermal growth factor, fibroblast growth factor, connective tissue growth factor, and insulin-like growth factor IGF-1.

These essential proteins regulate cell migration, attachment, proliferation and differentiation and promote extracellular matrix deposition. Growth factors in PRP promote hair regrowth by binding to their respective receptors expressed by stem cells and associated tissues of the hair follicles.

Does Hair PRP Treatment Have Risks?

Hair Prp Treatment is a method that is applied by processing the person's own blood and injected back into the problematic hair area of ​​the person. In hair PRP treatment, which does not contain any drugs and does not contain foreign substances, the substance taken from one person is injected into the same person, so it does not cause any allergic reactions or side effects.

Will There Be Pain During Hair PRP Procedure?

Hair PRP treatment is applied to strengthen hair and prevent hair loss. PRP hair treatment is not a very painful procedure. Before the application, solutions with anesthetic effect are applied to the area to be treated. This process, which is already done with very small needles, becomes quite painless with the effect of the solutions applied.

How Many Sessions of Hair PRP is Required?

Hair PRP treatment lasts between 4 and 6 sessions. For those with more serious problems, the number of hair PRP sessions can be up to eight. 3-4 weeks should be waited between Hair PRP sessions. After the hair PRP sessions are over, it should be repeated once in 6 months in order to continue to show its effect.

When Does PRP Show Its Effect on Hair?

The effect of PRP on the hair starts exactly after the 2nd month. The duration of the PRP effect on the hair may vary depending on the person or the size of the treated area.

Who can undergo Hair PRP Treatment?

Patients experiencing hair loss with intact hair follicles are typically good candidates for Hair PRP Treatment. These patients may have excessive hair loss, but they are not completely bald, so the sooner a person applies for Hair PRP, the better the results.

PRP hair loss treatment is a useful method for people who has thinning hair, and for anyone who experiences hair loss. Hair PRP is not applied to pregnant and lactating women. In addition, hair PRP is not performed on patients who are on blood thinners, cancer patients and people who have had cancer in the past.

Hair PRP treatment results are successful in both men and women. Hair PRP timing is very important. Especially in men, PRP results are more successful if they are done before baldness occurs.

To Whom PRP Is Not Applied?

It is not applied to those with a history of cancer, autoimmune disease, blood disease, infection and inflammation in the area where the application will be made, it is also not suitable for pregnant and breastfeeding women.